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Yesterday we saw the teaser trailer for Spiderman 3.
Here is what I learned:

Venom is definitely in it. There is a scene where the symbiote is attaching to Peter's arm. This hints at a Venom origin story closer to the Ultimate Spiderman version. In the original, the black suit was picked up on an alien planet during the first Marvel Secret Wars. In the Ultimate, the suite is a creation of Peter's father as a possible cure for cancer.
Either way, it feeds off emotion and makes Spiderman act erratically.
The trailer also shows Peter in a bell tower. In the comics, Venom was vulnerable to sonic energy and was first forced off Peter in a bell tower.
We see a shot of Topher Grace, who plays Eddie Brock. I would guess he is the childhood friend of Peter version from Ultimate Spiderman instead of the disgruntled co-worker version in the original.
The big question is the role Venom will play. In the comics he has been both nasty villain and anti-hero. It is possible by the end of the movie Venom and Spiderman will be working together against Harry Osborn and Sandman.
Another big question is: "What is the deal with Gwen Stacey?"
The teaser shows her clearly played by Bryce Dallas Howard.
Gwen has an extensive comic book history with Peter Parker. Widely considered to be his "true love" (even over Mary Jane), Gwen was certainly Peter's first love. Gwen was portrayed as being incredibly bright, identifying with Peter's intellect as opposed to shunning it. She preferred his personality over others such as Harry or Flash Thompson. Stacy was ultimately unable to escape the shadow of Spider-Man and his foes. A battle with Doctor Octopus (presumably deceased in Spider-Man 2) killed her father; Gwen blamed Spider-Man for his death.
Gwen was killed in the comics by Green Goblin in a scene mimicked in the first movie with Mary Jane. In the Ultimate Spiderman, Carnage kills her. As a side note, the Ultimate Spiderman Gwen Stacey had more of a punk/goth thing going on.
It's a safe bet that while Bryce Dallas Howard probably signed for three movies, she isn't counting on appearing in any others.
The last film had Harry finding his father's stash of evil. In the teaser, we see him using it.
His outfit is a little less super armor, a little more basic black with a half mask.
It does look like he is wearing some kind of goblin gloves.
We see Spiderman attack him, so we can assume that the alien may be controlling him. Or maybe Peter has gotten over not attacking his friends. Especially when they turn evil.
Of course, the whole Peter/Mary Jane/Harry/Gwen thing could cause anyone to turn evil.
The effect for Sandman looks good. With everything else going on it is easy to overlook the first announced bad guy. Sam Raimi has said that Sandman will have a family in this movie, so maybe he will be more than the simple thug he was in the comics.
He appears in the teaser in possibly the coolest moment -- pouring out of a sand truck and crushing some surprised cops.
We will get more trailers, I'm sure. This one didn't even actually show Venom, only the symbiote and the uber-cool black costume. We can expect to see him in the next trailer, I guess. The sad truth is that they have until May 4th, 2007 to finally show us Venom if they want to pull that E.T. stunt and not show him in anything until after the movie releases. I find that extremely unlikely, though, since action figures will hit the shelves in advance of the movie. What kid wouldn't want "Spitting Surprise Venom" immediately upon seeing the awesomeness?

After the trailer, we saw Superman Returns. I had a Diet Dr. Pepper.